Insulin and Other Proteins
نویسنده
چکیده
The normal modes have been calculated for structures having the dihedral angles of the four @-turns of insulin. Frequencies are predicted in the amide I region near 1652 and 1680 cm-’. The former overlaps the a-helix band at 1658 cm-l in the Raman spectrum, while the latter accounts for the hitherto unassignable band a t 1681 cm-’. Calculated amide I11 frequencies extend above 1300 cm-I, providing a compelling assignment of the 1303-cm-’ band in insulin and similar bands in other globular proteins.
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